Before using any drug for such purposes, always check information regarding how it works.
Know about dosage recommendations: for medical usage and for cutting or bulking phases.
Most importantly, be aware of safety considerations.
Synthetic anabolic androgenic steroids like Winstrol are prescription only, so purchasing the drug from underground labs or black-market resources can present a number of legal ramifications and safety issues. Click here to visit our recommended supplier.
Winstrol, Winstrol Depot, and its generic name Stanozolol is also known by other names including Stromba and Androstanazole, as well as:
Its molecular formula (C21H32N2O) is the best way to identify the specific drug because of its many synonyms and chemical names.
Before taking anabolic steroid pills, tablets, or injecting liquid solutions into the body, know how that drug effects certain body functions.
Anabolic steroids are often beneficial when used in medical scenarios, but are never recommended for bodybuilding or athletic performance enhancement. Though common in the bodybuilding world, Winstrol is mainly used today as a veterinary medication.
Known generically as stanozolol, it’s important to research positive and negative effects on the body before use.
This drug is classified as an estrane steroid that belongs to the kingdom of organic compounds and the superclass of lipids and lipid-like molecules.
As a steroid and/or steroid derivative with a molecular framework it’s defined as an aromatic heteropolycyclic compound.
Winstrol promotes anabolism or cellular growth, and androgenism, which encourages the development and maintenance of masculine characteristics.
Winstrol is synthetic variation of testosterone, a male hormone responsible for development and maintenance of male sex characteristics.
A small amount of endogenous (body-produced) testosterone is converted into a metabolite known as dihydrotestosterone or DHT.
Winstrol in oral tablet form or injectable (Winstrol Depot) is created from dihydrotestosterone. It’ perceived by bodybuilders to be quite a bit stronger in regard to effects than testosterone.
Winstrol, before it was discontinued for human use in the US, was recommended in the treatment of human hereditary angioedema.
This condition caused swelling in various parts of the body including the face, the throat, the genitalia, the extremities and some internal organs.
The drug was only used as a treatment to reduce the swelling and the frequency and severity of symptoms associated with the condition.
Today, Winstrol (Stanozolol) is considered a Schedule III controlled substance by the Food and Drug Administration.
It requires a prescription but in spite of the fact that it has been discontinued in many countries due to the severity of side effects associated with it, it continues to be one of the more popular anabolic androgenic steroids.
It’s used by athletes and bodybuilders to increase muscle gain and promote lean body mass.
Before taking any drug (oral, topical, or injection) be aware of its mechanism of action. What does it do in the body and how does it achieve those functions?
The main function of stanozolol – as a sex hormone binding protein – is its ability to bind to androgen receptors. Androgens are sex hormones that regulate development of male sex characteristics, much like testosterone.
Two steroid-binding sites were noted in a 2008 animal study (and therefore considered in humans as well) that function either as low-affinity glucocorticoid binding or stanozolol binding protein (which binds with laboratory created stanozolol androgen) sites.
In this 2008 study, stanozolol was observed to modulate glucocorticoid functions/activities in the liver.
Glucocorticoids are hormones that trigger synthesis or formation of glucose from amino acids and have an impact not only on metabolic functions, but immune system functions (anti-inflammatory) as well.
However, the capability of stanozolol, as a modification of dihydrotestosterone, doesn’t have quite the strong binding capability of testosterone or dihydrotestosterone.
The injection form, with a half-life of approximately 24 hours, and it’s relatively low binding protein capabilities make it potent in tissue building even in conjunction for the weaker capability to bind to androgen receptors.
Androgens, as briefly mentioned earlier, are sex hormones that determine the development and maintenance of male sex characteristics.
What does this mean for bodybuilders? Muscle building capabilities with lower androgenic side effects.
Winstrol, especially Winstrol Depot (injection form) doesn’t convert into estrogen, a process known as aromatization, where testosterone converts into estrogen.
It’s one of the most popular anabolic steroids most commonly available today in veterinary environments.
This is not to imply that stanozolol/Winstrol doesn’t have an influence on hormone levels.
While it is not known to cause the typical water retention or gynecomastia associated with other anabolic steroids with higher levels of androgenic properties, it does have androgenic characteristics.
Androgens, as male sex hormones, can have a stronger and negative impact on women.
In medical scenarios before the drug was discontinued, Winstrol/Stanozolol was recommended for the treatment of angioedema and some other types of anemia with an average dosage range of up to 6 mg a day divided into three even doses.
This was a prophylactic dosage only – intended to reduce the frequency and severity of symptoms for such conditions.
Bodybuilders often take higher doses than a recommended for the treatment of medical conditions. For example, bodybuilding Winstrol dosage recommendations for beginners start at 50 mg every other day.
An experienced steroid user may take as much as 100 mg a day. The higher the dosage, the greater the risk for a side effects and adverse reactions.
Such athletes claim that because of the short half-life of Winstrol in oral form, users don’t expect side effects, and if they do experience any, they’ll often be transitory in nature.
This isn’t always true, again depending on individual reactions, a person’s metabolism, and other contributing factors.
Expectations for results when using Winstrol will also depend on dosage, frequency of dosage, and how long the drug is used. Winstrol has a roughly five hour half-life when taken orally, and an average of 24 hours when taken in injection.
The half-life of a drug defines how long it takes to roughly half of the active ingredients in the drug to be absorbed and ‘effective’ in the bloodstream.
A number of factors can affect the half-life of the drugs including the age of the person taking it, their weight, their physical activity, their body composition, diet, and contributing issues such as health conditions.
A person’s reaction to Winstrol regardless of dosage depends on such individualized factors. Some bodybuilders and athletes may experience faster results than others.
Results can also differ between users even if they’re taking the same dosage and following the same dosage regimen.
As expected, stacking or combining Winstrol with other drugs during cutting or bulking phases common to bodybuilders may prove beneficial in promoting development of lean muscle mass and decreasing body fat levels, but may also contribute to a greater potential for side effects.
Hormone balances in the body must be carefully maintained. Altering testosterone, dihydrotestosterone and other endocrine gland hormone secretions can cause a number of unexpected side effects that may be difficult to get under control.
Winstrol, even at lower dosage ranges, has the potential to cause mild to very severe side effects.
Pay attention to what your body is telling you and always start at the lower dosage range to see how your body reacts to the drug before combining with other drugs or increasing dosage.
Because of its properties, stanozolol/Winstrol does not tend to aromatize, or convert testosterone to estrogen due to the activity of 5-alpha reductase, an enzyme commonly involved in the metabolism of steroids; 5-alpha reductase is an enzyme that metabolizes testosterone into dihydrotestosterone.
Although 5-alpha reductase does play a role in estrogen and androgen metabolism and the biosynthesis of bile acids, it is not affected by anti-androgenic drugs like finasteride.
Dihydrotestosterone is linked to male pattern baldness because the hormone has potent androgenic activities. High levels of dihydrotestosterone can also result in high levels of testosterone and vice versa. Dihydrotestosterone is linked to male pattern baldness.
Levels of dihydrotestosterone are affected by levels of testosterone. Hormone levels are monitored by the pituitary gland, known as the master gland of the body.
The pituitary gland, a very small (pea-sized) gland located deep in the brain, is in turn monitored and controlled by the hypothalamus, also in the brain.
If the hypothalamus determines that levels of testosterone are low, it releases a signal in the form of gonadotropin releasing hormone to the pituitary gland, which encourages the pituitary gland to manufacture and secrete luteinizing hormone into the bloodstream.
The luteinizing hormone travels to the male testes or a woman’s ovaries and stimulates production of testosterone. As testosterone blood levels increase, a portion of it (5% to 10%) is converted into dihydrotestosterone.
If levels of testosterone and in turn dihydrotestosterone are high, the hypothalamus and the pituitary work in conjunction to decrease signaling secretions of gonadotropin releasing hormone and luteinizing hormone.
When these carefully balanced levels get disrupted by exogenous drugs like anabolic androgenic steroids such as testosterone, unexpected results may occur.
Individuals who inject any form of testosterone, or any hormone for that matter, into the body when levels are already adequate risk potential side effects, hormonal imbalances, and even metabolic and organ function that can be difficult to get under control.
As an anabolic androgenic steroid, Winstrol side effects are in some ways similar to the side effects associated with other anabolic steroids. Winstrol was discontinued because of its prevalence for negative side effects. Among the most common:
Another embarrassing and quite frustrating and often painful side effect associated with Winstrol is priapism, or frequent and unexpected (and often untimely) erections.
A woman using Winstrol may experience virilizing side effects such as those associated with masculinization: a deeper, coarser voice, irregular menstrual periods and sometimes cessation of menstruation (amenorrhea), notable increase in hair growth on the face or body known hirsutism, and issues with acne.
Some women experience female pattern baldness.
Recent studies have focused on the potential of anabolic steroids like Winstrol to cause long-term damage to body functions and organs including cardiovascular conditions: left ventricular hypertrophy, reduction in left ventricular function, pulmonary embolisms, arterial thrombosis, myocardial infarction and sudden cardiac death.
When it comes to Winstrol/stanozolol specifically, a number of alarming alterations in the body and organ function have also been noted; some in animals, and some in humans including but not limited to liver damage and renal dysfunction.
A medical journal article (“Severe cholestasis with kidney failure from anabolic steroids in a bodybuilder“), defined a case study involving a 28-year-old German bodybuilder.
He had been taking “moderately high doses” of up to 50 mg of metandienone and injecting approximately 50 mg stanozolol intramuscularly every other day.
After discontinuation of the steroids, the young man’s condition deteriorated over a period of weeks until he developed renal failure.
After several weeks of treatment the young man did recover after being diagnosed with severe cholestasis and acute renal failure caused by his use of anabolic steroids.
Recent studies have determined that anabolic androgenic steroids can induce toxic hepatitis as well as alter psychopathology, i.e. ‘road rage’ and incidents of increased anxiety, anger, and aggression.
While there is no doubt that anabolic steroids can prove beneficial when carefully monitored by a physician and in the treatment of a medical condition, the potential for side effects and long-term adverse reactions are probable when used outside medical recommendations.
Recent studies have determined that even short-term use of anabolic androgenic steroids can contribute to long-range impact on organ health and body functions.
A few cases in point:
Take the time to read the medical case studies. These medical journal studies are real, as are the effects of anabolic androgenic steroids on the human body.
Bodybuilders often scoff at the warnings, but when it comes to Winstrol and other anabolic steroids, it pays to be cautious. Muscle mass gains achieved through use of anabolic androgenic steroids are not permanent in nature.
When steroids are discontinued, and depending on diet, exercise levels, and lifestyle, most often muscle mass gains will disappear.
Winstrol post-cycle therapy may help bodybuilders maintain some muscle mass gains during the off-season. Winstrol PCT routines and methods differ among bodybuilders.
For some, it can be difficult to get just the right balance when it comes to getting hormone levels back on track.
Some bodybuilders prefer using Clomid or Nolvadex, known as selective estrogen receptor modulators or SERMS that provide anti-estrogenic properties.
Using such drugs to help regulate hormone levels can contribute to additional side effects and disruptions to the metabolic and endocrine levels and functions in the body.
Recommendations for PCT may also differ depending on the source of information and recommendations. As with anabolic steroids, men and women will react differently to anti-estrogenic, anti-androgenic, and anti-progestational drugs.
The majority of these drugs are also prescription-only, compounding the difficulty and expense of maintaining gains.
At the risk of purchasing such drugs online or through black-market resources always be aware of the risk of contaminated, expired, and counterfeit products.
Poor manufacturing standards, low quality ingredients, and questionable if not downright dangerous fillers and ingredients in these drugs, especially from certain regions around the world such as India or Mexico, compound the dangers of not only serious risks to health, but legal ramifications.
Before using Winstrol, or any anabolic androgenic steroid, take the time to diligently research. Accessing bodybuilding websites, forum boards, discussion groups, and medical and scientific journals.
This is important when it comes to expectations in regard to results as well as the potential for Winstrol side effects and adverse reactions.