Popular opinion regarding Trenbolone claim it’s extremely effective in both bulking and cutting phases for those preparing for competitions, but it’s also popular among non-competing athletes.
Due to its very potency, its potential for side effects and adverse reactions are also very strong, but these effects are often ignored.
Before considering Trenbolone as part of a cycle, as a “quick fix”, or to accelerate results, be aware of its mechanism of action, what it was designed for, and how it affects the body.
While bodybuilders often look for dosage recommendations online, these recommendations will not come from physicians for obvious reasons.
Learn everything you can about Trenbolone before you use it, which will help you make an educated and knowledgeable decision regarding this specific anabolic androgenic steroid.
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Table of Contents
Trenbolone acetate is used in veterinary practices, and more specifically in the livestock industry as an anabolic agent.
In regard to use in bodybuilding circles, its two most popular forms are known as Trenbolone acetate and Trenbolone enanthate, but other names are also often used:
The basic molecular formula of each is slightly altered depending on the type of Trenbolone. For example:
At its most basic definition, Trenbolone is considered a “growth promoter”.
Each type of Trenbolone differs slightly in its molecular makeup, but basically, they all tend to provide the same benefits – although in stronger or weaker properties – as well a side effects regarding usage.
As a veterinary grade anabolic steroid, Trenbolone is found in cattle pellets most commonly sold under the brand Finaplix, though other brands are out there.
Each implant consists of 10 pellets of 20 mg Trenbolone (200 mg).
So one implant of Finaplix contains approximately 200 mg of Trenbolone that is meant for use on cattle prior to slaughter.
Underground and black market amateur chemists and drug manufacturers have found ways to adapt the Trenbolone steroid found in cattle pellets into oral tablets or injectable solutions that are then sold to humans.
The practice is not recommended. Not only is it illegal, but also such products range from high quality to abysmal in regard to benefits.
Why have bodybuilders turned to cattle pellets and animal steroids for human benefits?
Finaplix, also known as Finaplix-H or Finaplix-S, is designed for use in both heifers and steers.
The difference between Finaplix-H and Finaplix-S merely designates whether a specific form is meant for female cattle (heifers) or male cattle (steers).
Other competing brands such as Synovex and Revalor also manufacture Trenbolone acetate pellets with estrogen as an added component.
According to the manufacturer , the cattle pellets are designed to:
Keep in mind that the average weight of a steer is approximately 1,000 pounds.
Any underground labs or amateur drug manufacturer must use careful measurements to translate the potency of Trenbolone cattle pellets into a drug that is fit, and safe, for human use as an oral or injectable form of anabolic steroid.
Trenbolone is believed to provide a number of similar benefits in regard to human use as it does on animals, especially cattle:
However, too many red blood cells (polycythemia) can contribute to severe health risks and issues. It is also believed that Trenbolone may also have an effect on reducing cellular death (apoptosis).
Trenbolone and compounds similar to it are known to inhibit catabolism while stimulating anabolism, which results in enhanced muscle mass development, increased strength, speed, and power.
There is no medical basis for the use of Trenbolone for humans.
Bodybuilders and athletes wishing to determine dosage recommendations for black market Trenbolone must rely on recommendations provided by non-professionals.
A variety of bodybuilding websites do provide guidance for beginner, intermediate, and advanced anabolic steroid users when it comes to Trenbolone.
But every individual can, and often does, react differently based on a number of factors including age, weight, genetics, body composition, and so forth.
Trenbolone dosage recommendations are also based on the form of Trenbolone.
For example, the average recommendation for Trenbolone acetate for men can range 100 mg to 300 mg in injection form weekly, taken for anywhere from six to eight weeks.
In oral doses, 100 mg to 200 mg a day for the same length of weeks is recommended. Trenbolone enanthate dosage recommendations average 150 mg to 300 mg weekly for anywhere between six to 10 weeks.
Both forms of Trenbolone contribute to a number of androgenic and estrogenic side effects. Androgenic side effects are mainly gender specific.
Androgens are more often than not considered a male hormone because it’s associated with the production of testosterone. Androgens are related to gender specific or sex steroid hormones, at least chemically.
While the greatest majority of androgens are manufactured in the male testes, small amounts are also manufactured in female ovaries.
Androgens are also manufactured in small amounts by male and female adrenal glands, which sit like little hats on top of the kidneys.
The most powerful endogenous androgens, at least in humans, include testosterone and dihydrotestosterone. Two weaker androgens include dehydroepiandrosterone (DHEA) and androstenedione.
In basic terms, androgens trigger certain responses when they attach to or “dock” with specific cellular membrane receptors. This action instigates a variety of chemical signals depending on the location of the receptor.
Androgens can influence female sexual behaviors but are responsible mainly for controlling male sexual traits.
For example, a woman using androgens may develop male characteristics such as unusual growth of body hair in places it doesn’t normally occur (face and chest).
While a male taking androgens may experience female traits such as enlargement of breast tissues (gynecomastia), increased levels of estrogen and progesterone, as well as mood swings.
The drug (any form) is not recommended for women due to its potential to promote virilization (masculinizing) side effects.
According to a ranking of anabolic-androgenic steroids popularly used by bodybuilders to determine the potential efficacy of an anabolic steroid, Trenbolone acetate is rated as 500/500.
This means that its androgenic properties rate 500 (the highest level) as well as in its anabolic properties.
The same rating is given to a slightly different form of Trenbolone enanthate.
The difference between Trenbolone acetate and Trenbolone enanthate is its esters. Esters are often combined or attached to drug compounds to influence absorption rate or dispersal of the drug into the bloodstream.
Esters do this by encouraging the base drug to attach to specific cell receptors. The esters can also affect the half-life of a drug.
Half-life of a drug defines the approximate length of time that it takes any drug or drug compound to lose approximately one half of its strength or activity in the bloodstream.
A number of websites claim that use of Trenbolone in any form is relatively safe “when used responsibly”.
But many side effects have been noted to occur with use of any anabolic-androgenic steroid and the same applies to Trenbolone.
In addition to the estrogenic and androgenic side effects, there is a strong potential for liver damage.
While considered unlikely by many bodybuilders and circles, high doses and continuous, long-term use of anabolic steroids have resulted in serious liver toxicity.
Adverse reactions and contraindications do apply to any anabolic-androgenic steroid. Studies focusing on these negative effects are not just those that have been studied in the past.
Many of these studies apply to different types of anabolic androgenic steroids that include:
While many of these studies have been performed on animals, physicians today are seeing greater numbers of younger athletes with dangerous health risks due to damage to the cardiac muscle, the liver, and the kidneys – all caused by steroid use.
Of course, physicians are not going to engage in long-term studies regarding the negative effects that a veterinary drug can have on humans.
At the same time, potential users of Trenbolone (any form) should take these studies seriously, as a number of adverse reactions have been noted.
For example, in one study involving rats, a decrease in fat mass was noted but so too were reductions in high-density lipoprotein levels.
High-density lipoprotein or HDL is desired for optimal heart health. Hyperplasia and increased prostate masses were also noted, as was suppression of sex hormones and benign prostate hyperplasia.
Trenbolone acetate and Trenbolone enanthate are also often stacked or combined with testosterone in order to maximize benefits, but as drugs and dosages increase, so too do the risks for side effects.
Some of the most common side effects associated not only with Trenbolone, but with other anabolic-androgenic steroids are considered relatively mild and temporary.
Side effects may decrease as the drug is discontinued. Other side effects may be more severe and long-term in nature.
One of the most common side effects associated with the use of anabolic-androgenic steroids is a decline of natural, body-produced (endogenous) manufacture of testosterone.
This is the reason why many bodybuilders recommend stacking Trenbolone with testosterone at certain points in dosage cycles. The lack of endogenous testosterone can result in testicular atrophy or shrinkage of the testicles.
The saying, “use it or lose it” is a perfect example of what happens to the testes when they are no longer actively involved in manufacturing testosterone.
They atrophy or shrink, much like unused skeletal muscle on a person who is ill, elderly, or who avoids exercise.
Side effects associated with Trenbolone enanthate include but are not limited to:
More serious side effects have been linked to liver damage and cardiovascular damage, including hypertrophy, as well as ventricular arrhythmias .
A number of studies in medical journals have warned of the potentially toxic and damaging effect of not only Trenbolone, but other anabolic-androgenic steroids on the human body. For example, in regard to animal studies:
But what has that got to do with effects on humans? If bodybuilders want to translate the effects of Trenbolone on animals to human benefits, the same should be applied to potential side effects.
Anabolic-androgenic steroids have been linked to a number of alarming side effects and adverse reactions among younger men misusing and abusing anabolic steroids. Some of these individuals only used steroids for a very short time.
An incident in 2015 involved a wrestler using high doses with intramuscular injections of dexamethasone for six months, in addition to a variety of bodybuilding and nutritional supplements.
He was seen in the hospital for an acute myocardial infarction (heart attack).
And another: “New onset diabetes associated with bovine growth hormone and testosterone abuse in a young bodybuilder.” [Self-injected with Trenbolone acetate, testosterone, and bovine growth hormone]. (2011)
Nandrolone Decanoate has been linked to development of ventricular arrhythmias during endurance exercises in rats.
While a 2015 study (“Anabolic Androgenic Steroid (AAS) Related Deaths: autoptic, histopathological and toxicological findings.“) determined that prolonged use as well as abuse of anabolic androgenic steroids can severely damage the cardiovascular system.
This results in increased risks of sudden cardiac death as well as cardiac hypertrophy and myocardial infarction (heart attack) that were noted among 19 fatalities that occurred due to such misuse between 1990 and 2012, and yes, prior cardiovascular conditions were excluded.
Another study published in 2012 (“Anabolic androgenic steroids abuse in cardiac death and athletes: morphological and toxicological findings and four fatal cases.“) determined that three of these individuals experienced sudden cardiac death, one died due to congestive heart failure and one was diagnosed with concentric cardiac hypertrophy with vocalized fibrosis.
Such studies emphasize the severe risk of anabolic-androgenic steroid use even among young, otherwise healthy, fit, individuals.
Increasing numbers of scientific studies are reporting long-term organ damage caused by anabolic-androgenic steroid misuse, overuse, and abuse.
These studies are not to be ignored whether the results are determined from animal or human diagnostics.
While the risks of otherwise common anabolic-androgenic steroids are relatively common, using an anabolic steroid designed for cattle, which can weigh up to 1,000 pounds, on the human body is taking an excessive risk.
Trenbolone manufactured in underground labs often lacks quality ingredients, sterile manufacturing processes, or accurate measurements.
Components used to develop oral and injectable forms of Trenbolone are often received from countries where contamination, counterfeit product, and expired ingredients are common.
Regardless of claims of safety, Trenbolone in any form is not an anabolic-androgenic steroid that should be underestimated in regard to its potency or its potential for side effects.
Such side effects and adverse reactions as well as contraindications increase if an individual is not in perfect health or is taking medications for a prior condition including diabetes, cardiac issues, metabolic disorders, or endocrine disorders.
Pregnant and/or nursing women should avoid any use of anabolic-androgenic steroids due to the potential to contribute to fetal developmental defects and unknown effect on infant growth.
Always remember that the dosage recommendations for cycling Trenbolone in any form during a bulking, cutting, or post cycle therapy regimen may differ widely, and individual results as well as potential dangers to individuals are often case-dependent.
Recommended dosages that appear relatively safe for one individual may not apply to another based on different factors.
Some side effects of Trenbolone usage, as applies to any anabolic steroid, may be temporary in nature and often disappear when the drug is discontinued.
However, some serious side effects associated with anabolic-androgenic steroid use have been shown to cause long-term damage (even with short-term use) that can present years after the steroid use has been discontinued.