Esters are often attached to anabolic steroids and other drugs to regulate their absorption into the body/bloodstream as well as have an influence on the half-life or activity of a drug.
Nandrolone, as with other synthetic or laboratory created anabolic steroids, is a variation of the male hormone testosterone. Its use has been discontinued in the U.S.
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Nandrolone (nandrolone decanoate) has anabolic and androgenic properties known to stimulate the synthesis of red blood cells. This process is known as erythropoiesis.
Red blood cells are required for protein synthesis and are vital in transporting oxygen and nutrients to cells (and muscle cells and tissues) throughout the body.
Its main mechanism of action is to target and activate androgen receptors found in muscle tissues.
While it does this, it also has the potential to suppress or reduce luteinizing hormone secretions.
Luteinizing hormone is more commonly known as a women’s hormone – one that triggers ovulation.
It’s also found in males, responsible for the production of testosterone in the Leydig cells inside male testes.
Nandrolone is also considered a relatively mild anabolic-androgenic steroid with a moderate capability to trigger progestational side effects although with relatively low estrogen-like activities.
The decanoate ester encourages a slow release of Nandrolone for a longer half-life, which for some lasts two to three weeks.
The average is found anywhere between seven and 12 days post-injection. The half-life and effects of the drug will also depend on dosage.
Depending on where it’s purchased and the country of purchase, Nandrolone decanoate (basically a modified type of nandrolone) is typically available in a variety of injection dosage strengths: 25, 50, 100, or 200 mg per milliliter.
Individuals may have different reactions to the injectable drug depending on their weight, age, and of course, genetics, health status, and levels of physical activity.
Nandrolone side effects differ between individuals. Though rated as a relatively mild yet effective anabolic-androgenic steroid, Nandrolone side effects range from minor to alarming in regard to severity.
The side effects associated with Nandrolone usage also depend on whether the drug is combined with other drugs including testosterone, anti-estrogenic, anti-progestational, or other drugs and supplements used by athletes and bodybuilders.
Medical experts warn that chronic use of any anabolic-androgenic steroid including Nandrolone can cause potential health risks.
Women may experience virilization (masculinization) effects that may be irreversible.
Among the most common include menstrual irregularities, impotence, and growth of hair on the face, enlarged clitoris, and deepening voice.
Risk of premature cardiovascular disease and prostatic hypertrophy in men is possible. Liver damage is a possibility, as are psychiatric changes. Cardiovascular and hepatic (liver) damage is also possible.
Of course, a number of studies regarding potential damage have been performed on animals and have shown a negative impact on blood pressure, cardiovascular function, liver toxicity, and changes in various hormone levels, just to name a few.
A 2016 study determined that Nandrolone decanoate can contribute to “life-threatening ventricular arrhythmias” combined with high intensity endurance exercise.
Bodybuilders often scoff at the potential for Nandrolone side effects or adverse reactions of any anabolic-androgenic steroid use. They claim that with “responsible use” the risk of such side effects is vastly reduced.
However, Nandrolone side effects should not be ignored, as the use of any anabolic-androgenic steroid can contribute to long-term effects on health and wellness.
Recent studies and reports of heart damage, liver tumors, and kidney damage are increasingly found in medical journals domestically and abroad.
Medical researchers are attempting to determine the severity and potential of Nandrolone side effects or the side effects associated with other anabolic-androgenic steroids to trigger long-term damage that doesn’t show up until years after use.
Some of these reports are linked to individuals who used steroids for only a short period of time.
Bodybuilders often claim that such side effects are only possible among those with a predisposition to such conditions.
However, according to scientific research there are reports of sudden and often life-threatening Nandrolone side effects.
Always use caution when it comes to anabolic-androgenic steroids.
Nandrolone side effects are possible, no matter how many other drugs an individual takes to help reduce potential side effects.