Nandrolone decanoate is an injection form of the drug that is available by prescription only.
Every milliliter of that injectable solution contains 200 mg of Nandrolone decanoate.
Like other anabolic steroids, and Nandrolone is a synthetic variation of the male hormone testosterone.
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Nandrolone decanoate is known by a number of chemical names including 360-70-3; Deca Durabol; Decadurabolin, Retabolil, and more.
Chemically speaking, the decanoate ester is a salt form of nandrolone (an anabolic steroid) with a number of properties including anabolic, androgenic, and erythropoiesis (red blood cell creation) stimulating effects.
Nandrolone has the capability to find and activate a number of androgen receptors in muscle tissues while at the same time suppressing luteinizing hormone secretions.
In women, luteinizing hormone (LH) triggers ovulation, while in males it stimulates production of Leydig cells, which are vital in the production of testosterone within the testes (animal and human).
Before its use was discontinued in the US, Nandrolone decanoate was mainly used in the treatment and management of renal insufficiency anemia due to its potential to increase red cell production and hemoglobin levels.
Over the decades, studies have determined that the drug can cause liver damage such as Peliosis hepatis, which defines a condition where the splenic tissues are replaced by cysts filled with blood.
While in some cases this condition causes minimal effects, some have been linked to liver failure.
The issue was that these blood filled cysts were often undiagnosed until the liver failed and/or intra-abdominal hemorrhage occurred, a life-threatening situation.
In addition, development of tumors in liver cells were also reported. While the majority of these tumors were benign, some malignancies were reported.
Last but not least, it was noted that tumors that develop in the liver were more vascular in nature than other liver tumors, contributing to an increased risk of potentially life-threatening hemorrhage.
Nandrolone decanoate injections were intramuscular in nature and recommendations were to inject into the gluteal muscle.
For the treatment of renal disease anemia, dosages averaged 50 to 100 mg weekly for women and approximately 100 mg to 200 mg weekly for men.
The drug was discontinued if no improvement in the person’s condition was observed within six months of use.
In bodybuilding circles, dosages of Nandrolone decanoate far exceed recommended dosages for medical treatment.
Bodybuilding websites and suggestions on bodybuilding or steroid promoting websites recommended approximately 400 mg to 500 mg injections twice weekly.
These websites suggest inject into the thigh muscle or the upper arm.
Cycles used by bodybuilders injecting Nandrolone decanoate could last anywhere from three to six weeks in duration, followed by two weeks off before beginning the cycle again.
Before cycling with Nandrolone decanoate, be aware of the potential for severe and acute effects on numerous body organs and functions.
A number of recent studies have published such effects such as:
These are just a few. Bodybuilders like to say that studies on animals don’t equate to the same negative effects on humans, but they do.
After all, if a bodybuilder takes a veterinary grade steroid (such as Trenbolone or Equipose) because they believe it mimics the effect of accelerated muscle mass and feed efficiency, it stands to reason that the opposite is true.
Bodybuilders often scoff at the dangers, warnings, and potential side effects caused by not only nandrolone decanoate, but other anabolic steroids, but these risks should not be ignored.
Risks also increase when combined with other drugs to reduce unwanted side effects.
Stacking or combining other drugs with nandrolone decanoate is a common practice among bodybuilders and athletes in order to enhance benefits or decrease side effects.
Nandrolone decanoate is often stacked with testosterone. Careful balances of drugs must be maintained, as side effects of such combinations are often not only unexpected, but severe.
While Nandrolone enhances binding effects when attaching to androgen receptors (to greater degrees than testosterone) it nevertheless has a reduced effect on overall muscle growth.
As an anabolic agent, it has the potential to increase and develop muscle strength, and power, and inhibit catabolism while stimulating cannibalism, though less than expected in regard to size.
As an androgen receptor agonist it can produce androgen effects.
Numerous factors as well as methods regarding use can have an impact on overall results and potential for risks and side effects.
Individuals injecting Nandrolone decanoate should always use caution and discretion with use and watch for side effects and adverse reactions.